#paperhighlights Jun2021 #1

#paperhighlights Jun2021 #1

α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity Santos J, Gracia P, Navarro S, Peña-Díaz S, Pujols J, Cremades N, Pallarès I, Ventura S. Nat Commun. 12(1):3752 (2021)   doi: 10.1038/s41467-021-24039-2...
#paperhighlights May2021 #1

#paperhighlights May2021 #1

Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery S. Huecas, L. Araújo-Bazán, F. M. Ruiz, L. B. Ruiz-Ávila, R. Fernando Martínez, A. Escobar-Peña, M. Artola, H....
#paperhighlights May2021 #2

#paperhighlights May2021 #2

The Role of Non-Covalent Interactions on Cluster Formation: Pentamer, Hexamers and Heptamer of Difluoromethane Calabrese C, Temelso B, Usabiaga I, Seifert NA, Basterretxea FJ, Prampolini G, Shields GC, Pate BH, Evangelisti L, Cocinero EJ. Angew Chem Int Ed Engl....
#paperhighlights Apr2021 #1

#paperhighlights Apr2021 #1

Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase Cea-Rama I, Coscolín C, Katsonis P, Bargiela R, Golyshin PN, Lichtarge O, Ferrer M, Sanz-Aparicio J Comput Struct Biotechnol J....
#paperhighlights Mar2021 #2

#paperhighlights Mar2021 #2

Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity Modi T, Risso VA, Martinez-Rodriguez S, Gavira JA, Mebrat MD, Van Horn WD, Sanchez-Ruiz JM, Banu Ozkan S Nat Commun 12(1):1852 (2021) doi:...