# Highlights Paper 1 May 2025

«Enzyme Enhancement Through Computational Stability Design Targeting NMR-Determined
Catalytic Hotspots. «
 
Gutierrez-Rus LI, Vos E, Pantoja-Uceda D, Hoffka G, Gutierrez-Cardenas J,
Ortega-Muñoz M, Risso VA, Jimenez MA, Kamerlin SCL, Sanchez-Ruiz JM.
 
J Am Chem Soc. 2025 May 7;147(18):14978-14996. doi:
10.1021/jacs.4c09428.